Maintaining good oral health is easy with the Philips Sonicare e-Series Standard toothbrush heads. Designed to work with Advance, Essence, Elite, CleanCare, and Xtreme handles, these screw- on replacement brush heads remove up to 2x more plaque vs. a manual toothbrush. e-Series also features an angled neck and contoured bristles to help you easily maneuver the brush and focus on hard-to-reach areas where plaque can hide. The blue reminder bristles fade to let you know when it's time for replacement.